Posted by britney27 on March 26, 2008, at 19:09:32
In reply to Re: Parnate metabolites, posted by Quintal on March 26, 2008, at 15:04:36
> I think they were supposed to be mostly methamphetamine and PEA. People have been talking about this for years, but no real answers as yet. I once read a PubMed report of an autopsy where methamphetamine had been found in the body of a Parnate overdose, so it must be some truth in it. I noticed a similar effect re: dose escalation. At one point I was taking 120mg/day and it felt like getting a 'fix' from a stimulant like coke or meth. I've had a theory for a while that MAO inhibition 'augments' or amplifies the stimulant effect of the small amounts of amphetamine metabolites, so despite being produced in relatively small amounts, the metabloites actually have a substantial effect in practice. Of course I don't know if this is actually true.
>
> QHi Q, that is very interesting. Although I have never tried coke in my life somehow I get the feeling of what its like. Its almost like your whole body relaxes and you feel a sense of calmness...then comes the restlessness and I feel I have to move my legs up and down up and down.
So you are on 120mg a day. That is quite a large dosage. Have you been able to sustain that for a long time? I found at 100mg a day I was actually getting nauseous but the most worrying thing is that I was getting pain and tightness in my heart or heart pulpitations so I had to go back to 60mg and now I am building myself up again, lol. Do you ever get pain or tightness/restriction in the chest or heart pulpitations and is this something to worry about or is it just anxiety?
Also the first time I took it, I actually survived on 2-3 hours sleep and felt fully energised. Then I took a break from it because I actually couldn't afford it and started on it three weeks later but it actually has a sedating effect now instead of an energising effect which I think is quite weired.
cheers
Britney
poster:britney27
thread:819514
URL: http://www.dr-bob.org/babble/neuro/20080204/msgs/820058.html