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Re: Parnate LD 50 [xxx]? » britney27

Posted by Larry Hoover on March 24, 2008, at 8:19:01

In reply to Re: Parnate LD 50 [xxx]?, posted by britney27 on March 23, 2008, at 23:39:17

> Dear Larry, where did you get the gsk less XXXmg from? I tried to obtain that info on the internet but can't find it?

If you Google tranylcypromine and MSDS, it'll be on the first page.

> What does that exactly mean anyway, does it mean anything less than XXXmg a day is safe?
>
> cheers
>
> Britney

There are a number of interpretive issues to consider. First, the toxic amount is stated in ambiguous terms. Less than XXX? How much less? I don't recall seeing a vague statement like that one on an MSDS, ever before. Also, this figure is for another species, not even in the same Order as we are, i.e. not from a primate. Generalizing toxicity from this vague information is risky.

But that's why I focussed on the symptoms of toxicity. Frankly, it doesn't matter one iota what the statistical dose for toxicity happens to be, when one individual is making that personal assessment of toxicity. 10,000 other people might get away with taking a particular dose, but if it creates symptoms of toxicity in *you*, then that's all that matters. For you, that's all that matters.

Lar

 

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poster:Larry Hoover thread:819514
URL: http://www.dr-bob.org/babble/neuro/20080204/msgs/819635.html