Posted by bulldog2 on May 18, 2010, at 17:38:26 [reposted on May 20, 2010, at 18:36:22 | original URL]
In reply to Re: Gone with trimipramine, posted by linkadge on May 18, 2010, at 14:16:35
> Trimipramine has the same opioid like effects as other TCA's. Even though it doesn't inhibit monoamine uptake, who says this matters?
>
> Trimipramine has affniity for MAO-B as well as the DAT transporter. It also shares the common affinity for monoamine receptors (acetylcholine, serotonin, histamine etc.)
>
> I would strongly hesitate in saying that surmontil is not an antidepressant just because it doesn't inhibit the classic monoamines (serotonin, norepinephrine).
>
> After all, its this flawed logic that produces the so called "tianeptine paradox"
>
>
> LinkadgeYes it is possible it might have ad properties. There also was someing wikipedia that inidcated it might have strong neuropletic properties.
poster:bulldog2
thread:948075
URL: http://www.dr-bob.org/babble/neuro/20100223/msgs/948082.html