Posted by med-amorphosis on May 18, 2010, at 11:13:10 [reposted on May 20, 2010, at 18:36:21 | original URL]
In reply to Re: Imipramine really that good? » gman22, posted by med-amorphosis on May 18, 2010, at 5:53:58
Surprisingly, my pdoc's first suggestion was to add bupropion the the mixture, keeping the lofepramine too. But I opted for a switch in TCAs 1st. He was willing to try 3 TCAs starting with trimipramine (Surmontil). If that fails then amitryptyline and finally, imipramine. Although imipramine would be used after various other options have been tried- ie a last resort.
So im swapping 210mg/day lofepramine to 25mg trimipramine, slowly titrating to 100mg at week 3.
Any trimipramine experiences anyone would like to share? Any knowledgable babblers explain how its meant to work? Apart from re-uptake inhibition the remainder of its actions slightly baffle me in this description:
http://en.wikipedia.org/wiki/Trimipramine
maybe its not the best source. Can anyone explain its effects in plain english (or there abouts)?med
U.K.resedent
Ills: Avoidant Personality Disorder, major depression, addictive personality
Regime: 90mg isocarboxazid, 4mg clonazepam, 50mg trimipramine-titrating to 100mg
poster:med-amorphosis
thread:948075
URL: http://www.dr-bob.org/babble/neuro/20100223/msgs/948075.html