Posted by med-amorphosis on May 19, 2010, at 14:16:47 [reposted on May 20, 2010, at 18:36:24 | original URL]
In reply to Re: Gone with trimipramine, posted by bulldog2 on May 18, 2010, at 17:38:26
> > Trimipramine has the same opioid like effects as other TCA's. Even though it doesn't inhibit monoamine uptake, who says this matters?
> >
> > Trimipramine has affniity for MAO-B as well as the DAT transporter. It also shares the common affinity for monoamine receptors (acetylcholine, serotonin, histamine etc.)
> >
> > I would strongly hesitate in saying that surmontil is not an antidepressant just because it doesn't inhibit the classic monoamines (serotonin, norepinephrine).
> >
> > After all, its this flawed logic that produces the so called "tianeptine paradox"
> >
> >
> > Linkadge
>
> Yes it is possible it might have ad properties. There also was someing wikipedia that inidcated it might have strong neuropletic properties.Well I can say that the Surmontil brand is ONLY marketed as an AD here, or with associated anxiety. How can you question its AD abilities when its been used and marketed as such for so long?
U.K.resedent
Ills: Avoidant Personality Disorder, major depression, addictive personality
Regime: 90mg isocarboxazid, 4mg clonazepam, 50mg trimipramine-titrating to 100mg
poster:med-amorphosis
thread:948075
URL: http://www.dr-bob.org/babble/neuro/20100223/msgs/948091.html