Posted by bulldog2 on May 18, 2010, at 13:36:54 [reposted on May 20, 2010, at 18:36:21 | original URL]
In reply to Gone with trimipramine, posted by med-amorphosis on May 18, 2010, at 11:13:10
> Surprisingly, my pdoc's first suggestion was to add bupropion the the mixture, keeping the lofepramine too. But I opted for a switch in TCAs 1st. He was willing to try 3 TCAs starting with trimipramine (Surmontil). If that fails then amitryptyline and finally, imipramine. Although imipramine would be used after various other options have been tried- ie a last resort.
>
> So im swapping 210mg/day lofepramine to 25mg trimipramine, slowly titrating to 100mg at week 3.
>
> Any trimipramine experiences anyone would like to share? Any knowledgable babblers explain how its meant to work? Apart from re-uptake inhibition the remainder of its actions slightly baffle me in this description:
> http://en.wikipedia.org/wiki/Trimipramine
> maybe its not the best source. Can anyone explain its effects in plain english (or there abouts)?
>
> medFrankly sounds like more of a sedative than an antidepressive.
poster:bulldog2
thread:948075
URL: http://www.dr-bob.org/babble/neuro/20100223/msgs/948078.html