Posted by sowhysosad on April 8, 2009, at 21:36:35
In reply to Re: Do SSRI's cause dopamine depletion, posted by Alexanderfromdenmark on April 8, 2009, at 17:28:11
> But what is the significance of sensitizing d2 receptors? Generally I seem to find that studies show that ssri's downregulate dopamine, as such there is less dopamine and not more, sensitizing d2 receptors ot not.
>
> on the subject on dopamine depletion take a look at this.
>
> http://ajp.psychiatryonline.org/cgi/content/full/162/9/1755I'm not entirely sure what the significance is Alexander and the research is quite vague, just speculating that it "contributes to the antidepressant effect" in some way. I'd imagine it makes the brain more sensitive to the effects of what dopamine remains, and thus helps with energy, concentration and sleep regulation.
Interesting article about dopamine depletion. I've suffered some of those symptoms recently, which lends weight to my theory that my dopamine levels are low.
poster:sowhysosad
thread:883495
URL: http://www.dr-bob.org/babble/neuro/20090129/msgs/889572.html