Posted by desolationrower on March 4, 2009, at 20:54:14
In reply to Re: Do SSRI's cause dopamine depletion, posted by myco on March 4, 2009, at 16:41:13
i'm not sure we know things return to normal, sris increase serotonergic dendritic branching, and i don't know how much that reverses. generally that is considered part of the positive effect reversing depression. there is not much in the way of long-term research on antidepressants. its expensive enough doing a 6 week trial. this is one reason there is little research done on balding, it takes 6 months for effects to be seen, which makes any trial quite costly.
some 5ht neurons exert an inhibitory effect on DA neurons.
there are 5ht receptor antagonists that have positive effect on DA levels in some situations. The other main avenue is more direct activation of DA neurons, something like bupropion is the most common option.
-d/r
poster:desolationrower
thread:883495
URL: http://www.dr-bob.org/babble/neuro/20090129/msgs/883822.html