Posted by ed_uk2010 on May 17, 2010, at 15:38:39
In reply to Re: Imipramine really that good? » ed_uk2010, posted by med-amorphosis on May 17, 2010, at 15:11:22
>So why has my pdoc included it in the list of TCAs he 'will' consider adding to my MAOI, as well as amitriptyline?
I must say that I am very surprised.
>Anyway, imipramine is greatly more potent as an NRI than SRI, esp as its broken down to desipramine anyway. No?
Imipramine itself acts as a moderate SRI and a NRI. Desipramine is an NRI. I would be very concerned about combining imipramine with any of the MAOIs. Fatalaties have been reported.
eg. Imipramine added to the MAOI tranylcypromine (Parnate)...
http://www.ncbi.nlm.nih.gov/pubmed/12927331
poster:ed_uk2010
thread:947687
URL: http://www.dr-bob.org/babble/20100514/msgs/947701.html