Posted by rgb on September 19, 2009, at 11:34:58
In reply to Re: The Final Pathway To The Dopaminergic Pot Of Gold?, posted by Sigismund on July 3, 2009, at 1:42:01
> Off the top of my head I wonder about very low dose Dexedrine and Ritalin with agomelatine at night.
Interesting idea (sadly, I don't have access to either...).
>
> I worry a bit about 5ht2A blockade. For some reason I feel better about 5ht2C. Probably some prejudice in favour of hallucinogens.Seconded. I was under the impression that 2A *increases* dopamine release and 2C decreases it, but I don't know where I got that impression :)
To confuse things further, apparently different agonists can activate the 2A receptor in different ways, explaining why only some of them cause psychedelic effects:
poster:rgb
thread:904542
URL: http://www.dr-bob.org/babble/neuro/20090701/msgs/917683.html