Posted by g_g_g_unit on May 25, 2009, at 10:07:08
In reply to Re: Please, quick explanation?, posted by desolationrower on May 22, 2009, at 15:29:03
well, i have been trying to find dosing guidelines and it's proving really difficult (mainly because my pdoc doesn't know anything about the drug, and most pharmacists are hesitant about advising regarding off-label; i even rang the company directly and couldn't get much out of them).
when i said the drug was increasing addictive behaviours, there wasn't much pleasure or euphoria behind it; it was more like a hard-edged stimulation that was in its own way inhibiting concentration because my mind felt like it was working too quickly (i.e. non-selectively imprinting detail etc.). i couldn't work out whether (as a sign of too much D2) that meant i should lower or raise the dose; i was wondering if the drug's D2 action is maybe more predominant at lower doses and then the NMDA effect kind of overtakes and begins to modulate it at higher doses? but then i realised that due to the 60(?) hour half-life i probably also haven't achieved a steady blood plasma level. was it you d/r who in another thread reported that the drug has an early amphetamine effect which soon fades?
anyway, i am wondering now whether i should try splitting the 10mg between morning and night and see if i can get some benefit from that, once the more stimulating effect (hopefully) fades. otherwise if higher doses prove to be more calming, it would probably be worth pushing to 20mg, and sitting it out until i had a steady blood plasma level. it's just that now that i'm beginning to finally see some benefits (the drug has completely vanquished the brain fog that's plagued me for the past year, and which had left me pretty much unemployed) i'm starting to get impatient, though i know i shouldn't rush it. this is just such a huge breakthrough for me that i don't wanna mess it up ..
poster:g_g_g_unit
thread:895324
URL: http://www.dr-bob.org/babble/neuro/20090129/msgs/897572.html