Posted by SLS on April 23, 2009, at 22:38:29
In reply to How much time for the MAO Inhibition?, posted by tepi on April 23, 2009, at 22:23:30
>
> Does somebody knows how much times its needed to
> reach the Max ihhibition of the MAO using Nardil or Parnate or any other MAOI.... 4 weeks ? 8 weeks ?
> Im planning things for my life...
>
> Thank you GroupWild guess - 10-14 days at a steady dosage?
Definitely not 4-8 weeks.
After you reach the percentage of inhibition that is right for you, you need to expect to remain there for 3 weeks to see some improvement. This may represent the time necessary for the compensatory changes that occur in receptor binding. There is approximately a 2 week turnover in receptors, so one might suspect changes in receptor numbers to be involved in the antidepressant response, and why that response is latent to the initial drug exposure.
- Scott
poster:SLS
thread:892451
URL: http://www.dr-bob.org/babble/20090416/msgs/892454.html