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Re: Exotic Meds for Treatment Resistant Depression » SLS

Posted by uncouth on September 27, 2008, at 17:04:35

In reply to Re: Exotic Meds for Treatment Resistant Depression » bulldog2, posted by SLS on September 27, 2008, at 9:13:08

scott,
what do you believe to be the most effective A/D adjunct in your mix. e.g., if you had to choose just parnate and one other drug for the depression, what would it be?
i'm on parnate and did a 2 week trial of abilify with some old stock i had from trying the drug years ago. i found that it had a profound affect. to me, all A/D tune up the 'hardware' -- speed it up or slow it down or whathaveyou, while abilify was like a 'software' upgrade. its hard to explain but the antipsychotic effects definitely kicked in at 10mg for me, although i'm not psychotic (just BP2), i do get obsessive and ruminatively depressive thoughts.

im' curious why you are on lamictal AND abilify. and what dose of abilify and lamictal? from my understanding abilify is a pretty good mood stabilizer in its own right....so what are you using lamictal for?

in addition, how much NAC do you take, and how do you take it during the day, and how much vitamin C do you take with it? (and are you concerned about excess vitamin C).

thanks,
uncouth

> > > > I have treatment-resistant depression and am interested in hearing about experiences with the more exotic medications such as opiates, ghb, ketamine, alzheimers meds, etc. Please share your experiences if you have them.
> > >
> > > Have you tried an MAO inhibitor yet? What were the results?
> > >
> > > My regime comprises the following:
> > >
> > > Parnate
> > > nortriptyline
> > > Lamictal
> > > Abilify
> > > NAC
> > >
> > >
> > > - Scott
> >
> > You switched from nardil to parnate?
>
>
> It is nice of you to notice.
>
> :-)
>
> Yes, I made a switch from Nardil to Parnate. I had reached a sticking point with Nardil. Although I have been on Parnate several times before, I never combined it with the other drugs I am taking. In fact, the only truly robust response to treatment I experienced was with a combination of Parnate and desipramine. It was 1987, and I managed to stay well for nine months. My doctor subsequently had me discontinue both drugs when I appeared to become manic. Unfortunately, I relapsed two months later. To make a long story short, I never responded to that combination treatment again.
>
> I am looking forward to losing the 50lbs of weight that Nardil put on me.
>
> Many doctors are of the opinion that Parnate is a better choice for treating bipolar depression than is Nardil.
>
>
> - Scott

 

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