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Re: Exotic Meds for Treatment Resistant Depression » Bob

Posted by SLS on September 28, 2008, at 6:41:44

In reply to Re: Exotic Meds for Treatment Resistant Depression » SLS, posted by Bob on September 27, 2008, at 21:45:09

> > My regime comprises the following:
> >
> > Parnate
> > nortriptyline
> > Lamictal
> > Abilify
> > NAC
> >
> >
> > - Scott

> Wow. You've made some major changes to your drug regimen.

I consider it to be a no-lose move. If I don't respond as well to Parnate as I expect to, I might even give Marplan a whirl before returning to Nardil.

> As for the Nardil induced weight gain, don't you think Nortriptyline would cause weight gain in the long run also?

It does, and has. However, I find that I have success at managing my weight through diet with nortriptyline. I have lost 10 pounds in less than two weeks. Nardil is much more stubborn for me.

> I thought pretty much all tricyclics were known for that.

Pretty much. I think amitriptyline is probably the worst. However, I don't think they are universally worse than SSRIs. Desipramine is relatively weight-neutral. The problem with desipramine is that it tends to leave me with residual anhedonia. A pinch of serotonin is probably helpful to me.

Where are you at with things?


- Scott

 

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