Posted by the kindling effect on February 13, 2006, at 16:01:25
In reply to Re: ATTN: fenix, posted by fenix on February 13, 2006, at 11:37:17
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> > Basically the medicines to try are: propranolol, benzodiazepines, opiates, dopamine-depleters.Be careful with Reserpine as it's irreversible.
Tetrabenazine(Nitoman) is supposed to be quite a bit safer.
THey are actually mono amine depleters, so not just dopamine.Sort of the opposite of an AD, not something I look forward to. And as two neuros told me not a pretty sight. THey suggested it only be trialed in hospital because depression and parkinsonism are the main side effects, and suicide attempts aren't that uncommon.
Yeah those are the standards. diferent TA cases respond to different things. Plus akathisia can be a symptomof a lot of neurological disorders and those generally need to be ruled out(that kinda freaked me a little.)> >
> > Propranolol will most likely do nothing.
Depends on the case. I don't know why they ignore the other beta blockers so much, simply because Propranolol is the most lipophallic.There are other beta blockers as well as combo beta/alpha blockers. For me Nadolol was quite different form the others. If you have underlying depression it's not the greatest. Clonidine should also be tried(I had partial success,esp. physically and with my mild dystonias). My biggest deal is to try and get to an on-going doctor before I start back in on ADs and APs again and make it worse.
Benzos, they may help a little at most...
Varies person to person. Why clonazepam for you and lorazepam for me? Who knows.(although cloxazolam a Brazilian benzo was probably strongest I've tried.)
Opiates, well, they would at least make you feel better but they aren't very helpful concerning the 'painful agitation' of the kind that Tardive Akathisia gives.You never know what'll happen til it's tried, especially in my case so I'm told the way my brain has been tweaked and twisted. I've wondered about buprenonorphine since it's being used a lot for depression currently. Possible option? Even tylenol 3s with codeine have proved successful. The short half-life isn't great though as with so many of the treatments.
Dopamine depleters... this might be useful, but again, only to an extent.
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> > To summarize, at the least you can reduce the pain of TA by a fraction; at the most, you can reduce the pain of TA by a larger fraction.
2% is a bi rduction for me. I've also got Tardive tics know wihich I'm told are simply an extension of the TA. They also kept going on about choreatic movements.(Wilson's and Huntigton's have been ruled out already.)
In other words, to be frank, you can't really do sh*t about it.
Yeah you're probably right about that, although that sounds more like a doctor that doesn't have it talking.
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> > Let's hope there is some more research done on this.
I'd rather be a part of it than sitting around(OK pacing around) trying to be patient.
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> > Also, you should just search on the internet for TA if you are feeling brave, you can read much about it and what has been tried for it.
Done a long time ago and Ed UK provided me with some other sucess stories. Nothing brave about it. That's psychological. Dealing with the TA nightmare kind of overshadow everything else.
This is assuming of course, that you can bare the pain of akathisia long enough to do this.
Sometimes yeah, sometimes no. TA doesn't gove me a lot of choice. And as I'm sure you know fighting it can sometimes make things worse.
> Confound it, I keep forgetting to add things so I have to keep posting... this should be the last one here.I have a simlar problem. Filling out a a simple form becomes an over-written ,garagantuan task in indeceisive and tangents.
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> Basically, I hope what I have just told you doesn't make you lose hope.
Don't worry guy, my mind and I make that call.
Published studies are always behind anyways. It's the current experimentation we need to look at. And nothing you've told me is new. THe only hope I was holding out was a forward to a knowledgable doctor who's not bogged down in a public health system(eg. Canada,Cuba & North Korea-the 3 remaining countries in the world where you don't have the option of private health. And out of the 3 probably Canada & North Korea are worst off. I've already spent 4 weeks in a psych hospital in Toronto and they were clueless about akathisia)There is a chance that one of the things I mentioned (or maybe something else) will reduce the symptoms enough so that you will feel a lot better.
'A lot better'. Sounds pretty hopeful to me. That's verging on miraculous for TA.>
> And... sometimes, going back on a certain AP will reduce the symptoms quite extensively, however, it was advised to me that this is risky, mainly because in the long-term the symptoms will most likely worsen if you continue AP usage, and you could develop other things along side of TA.
Yep, I know that one. But it gave me my life back for awhile. Already developed tics and junk along with some cognitive stuff. But enduring lifelong TA is simply not an option.
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> Lastly, you could see about a legal angle at the least. People have sued and won concerning Tardive Dyskinesia, however, I am not very encouraged still...
There's only been one lawsuit in Canada for TD and that was iin 2000 regarding a geriatric women and a doctor who gave her Haldol.
Tardive Akathisia is very subjective and with Dyskinesia you can at least see the physical damage done. With bad TA it's hard to miss the physical stuff too; the person looks like they're going to piss their pants. The writhing can give away some of the...pain too.Ironically, Tardive Akathisia is probably worse than its 'cousin'.
Probably? I'd say definitely. Apparently a lot of peolpe with orofacial dyskinesias aren't even aware they're making the movements. It's being can't simply a 'variant' of TD now. So technically you have TD. Respiratory Akathisia has been identified now (that wasn't fun) and apparently bruxism it's being said is simply an early sign/form of akathisia.
Put bluntly, akathisia is some serious sh*t that too many psychiatrists don't take seriosly. For me it was "does the benzo/beta blocker help with the akathisia at night" sure doctor, it gets me to to sleep. "No problem than" . Yeah right.
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poster:the kindling effect
thread:604046
URL: http://www.dr-bob.org/babble/20060212/msgs/609229.html