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Re: Paxil losing effect? » Jbee

Posted by JahL on August 10, 2004, at 19:13:13

In reply to Paxil losing effect?, posted by Jbee on August 9, 2004, at 22:30:58

> I’ve been on paxil for a few years and I believe that it’s begging to lose it’s effect on my
> SAD. Have you ever heard of this? Could it be related to my switch to generic paxil?
> Info please?

Hi Jbee.

Sounds like good old fashioned 'poop-out', where the medication simply ceases to work. It's a widely known phenomenon. I'm not sure what the consensus of how to proceed is exactly, but I think switching to another antidepressant is a popular move. Just how successful this approach is a matter of contention, but I think as with most medications, efficacy varies widely from person to person.

If it is poop-out you are experiencing, I am truly sorry. The only time I have ever felt normal was when briefly euthymic on a variety of SSRIs. I got about 2 months of normalcy before the dreaded poop-out kicked in. *ucker.

The switch to generics should theoretically make no difference; they are identical in chemical make-up to brand versions. If it was me, superstition would compel me to switch back to brand name, just to check that the loss of efficacy was not down to this. But then I'm a little paranoid. And desperate.

Best,

J.


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