Posted by Ritch on January 21, 2003, at 0:05:29
In reply to Re: Older drugs vs. newer drugs... » Ritch, posted by Jumpy on January 20, 2003, at 21:41:37
> > Jay, the TCA's are can be dangerous in overdose and do cause cardiac conduction problems in quite a few people (at higher doses). The number one thing I don't like about TCA's is the orthostatic hypotension. I even got that with Remeron and it was the number #2 side effect (besides duhhness) that I didn't like about the Remeron. Nortriptyline was the easiest in that regard, and nort. is probably the only TCA I would ever retry.
>
> I though imipramine's side effects were similar to nortriptyline's. In the test tube, imipramine might have more affinately for receptors causing certain side effects. But in vivo, people have a good amount of the imipramine converted to desipramine, which for many has less side effects than nortri.
>
> J
>I had an *excellent* anti-ADD response with taking low-dose desipramine, but had *much* more blurred vision, tachycardia, and dizziness, that nortiptyline didn't cause, but I needed to take something else with the NT to get the anti-ADD response as robust as with desip. (in my case low-dose Zoloft).
poster:Ritch
thread:136591
URL: http://www.dr-bob.org/babble/20030119/msgs/136829.html