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Re: Older drugs vs. newer drugs... » Ritch

Posted by Jumpy on January 20, 2003, at 21:41:37

In reply to Re: Older drugs vs. newer drugs... » jay, posted by Ritch on January 20, 2003, at 10:00:24

> Jay, the TCA's are can be dangerous in overdose and do cause cardiac conduction problems in quite a few people (at higher doses). The number one thing I don't like about TCA's is the orthostatic hypotension. I even got that with Remeron and it was the number #2 side effect (besides duhhness) that I didn't like about the Remeron. Nortriptyline was the easiest in that regard, and nort. is probably the only TCA I would ever retry.

I though imipramine's side effects were similar to nortriptyline's. In the test tube, imipramine might have more affinately for receptors causing certain side effects. But in vivo, people have a good amount of the imipramine converted to desipramine, which for many has less side effects than nortri.

J


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URL: http://www.dr-bob.org/babble/20030119/msgs/136809.html