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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by Frustratedmama on July 2, 2009, at 11:44:08
I am trying again to get someone to answer how stimulants work..... What do they do? Please help.... thanks
FM
Posted by Sigismund on July 2, 2009, at 15:09:57
In reply to PLEASE RESPOND THIS TIME, posted by Frustratedmama on July 2, 2009, at 11:44:08
This may be a bit difficult
http://www.dr-bob.org/babble/20071204/msgs/798870.html
It's about tolerance to stimulants.
Posted by Sigismund on July 2, 2009, at 15:53:12
In reply to PLEASE RESPOND THIS TIME, posted by Frustratedmama on July 2, 2009, at 11:44:08
> Amphetamine appears to exert most or all of its
effect in the CNS by causing release of biogenic
amines, especialy norepinephrine and dopamine, from
storage sites in nerve terminals. It may also slow
down catecholamine metabolism by inhibiting monoamine
oxidase (Hardman et al., 1997).
Posted by Frustratedmama on July 2, 2009, at 18:51:15
In reply to Re: PLEASE RESPOND THIS TIME, posted by Sigismund on July 2, 2009, at 15:09:57
THANK YOU!!!!!!
Posted by Sigismund on July 2, 2009, at 20:23:16
In reply to Re: PLEASE RESPOND THIS TIME, posted by Sigismund on July 2, 2009, at 15:53:12
I could be quite wrong, but I wonder if cocaine and Ritalin inhibit the reuptake of dopamine.
Posted by floatingbridge on July 2, 2009, at 22:06:33
In reply to Re: PLEASE RESPOND THIS TIME, posted by Sigismund on July 2, 2009, at 15:09:57
Thank you so much, Sigismund!
fb
(yes, it it a bit dense for me, but I'll re-read. I'm starting to get a glimmer about how some of these substances work, with repeated reading here on Babble.)
Posted by metafunj on September 13, 2009, at 2:12:05
In reply to Re: PLEASE RESPOND THIS TIME, posted by Sigismund on July 2, 2009, at 20:23:16
Cocaine blocks the reuptake of dopamine, norepinephrine, and serotonin. I'm not sure where the brain damaging effects come in.
Ritalin blocks dopamine and to a lesser extent norepinephrine receptors. Also through a process call phosphorylization it reversed the dopamine transporter to release dopamine from the vesicles into the synapse, instead of removing dopamine from the synapse.
This is the end of the thread.
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