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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by DontNoMuch on February 29, 2008, at 15:57:44
After 18 months, Lexapro, Zoloft, Effexor, Wellbutrin, Cylexa, off and on and off again . . .
Doc prescribed Nardil this past week. 15mg 2x a day for 7 days, then 3x a day for 7 days, then 4x a day -
I am on my 4th day and keep wondering when I will feel it working. Right now, just stare at screen, feel really sad, hopeless almost.
The best med I've had yet is Provigil, still taking it. 100mg / day is sufficient for me. It keeps me awake, even if I am not being very productive, beats sleeping all day.
I feel as though I am in a fog.
Am excited about Nardil, just really hope that it works.
Posted by Phoenix1 on February 29, 2008, at 22:48:05
In reply to Nardil for Depression, posted by DontNoMuch on February 29, 2008, at 15:57:44
> After 18 months, Lexapro, Zoloft, Effexor, Wellbutrin, Cylexa, off and on and off again . . .
>
> Doc prescribed Nardil this past week. 15mg 2x a day for 7 days, then 3x a day for 7 days, then 4x a day -
>
> I am on my 4th day and keep wondering when I will feel it working. Right now, just stare at screen, feel really sad, hopeless almost.
>
> The best med I've had yet is Provigil, still taking it. 100mg / day is sufficient for me. It keeps me awake, even if I am not being very productive, beats sleeping all day.
>
> I feel as though I am in a fog.
>
> Am excited about Nardil, just really hope that it works.Hi Dontdomuch,
I was in your situation a few months ago. Tried all the ssri's and atypical AD's and various combos, but nothing helped. Nardil has been a true lifesaver. I can honestly say that I feel 100% better. It may take 4-6 weeks after you reach 60mg to feel a real improvement. It's also possible that Nardil won't work for you, but it seems to be pretty darn effective for many people if they don't suffer too many side effects or are willing to tolerate them.
The fogginess may be a side effect of nardil or may just be due to lack of sleep. Do you have any sleeping meds? If not, ask your pdoc for something. For many people such as myself, the insomnia doesn't improve much over time.
So maybe stick with it for a while and try to be patient. It can take a wile for Nardil to kick in, even though you read stories of people who felt great in the first week. Good luck, and keep me updated with your progress!
Phoenix1
Posted by cumulative on March 1, 2008, at 12:20:16
In reply to Nardil for Depression, posted by DontNoMuch on February 29, 2008, at 15:57:44
It can take a while to work, and you may have to titrate up to 1mg/kg (as it mentions in the monograph), but once you get past all that the effects can be robust. Like Phoenix said, it's worth taking care of the side effects (which seem to lessen or disappear with time for most people) with augmentation, especially the sleep issues.
Posted by dontnomuch on March 1, 2008, at 18:51:41
In reply to Re: Nardil for Depression, posted by cumulative on March 1, 2008, at 12:20:16
> It can take a while to work, and you may have to titrate up to 1mg/kg (as it mentions in the monograph), but once you get past all that the effects can be robust. Like Phoenix said, it's worth taking care of the side effects (which seem to lessen or disappear with time for most people) with augmentation, especially the sleep issues.
*********
Well, I was taking Cymbalta and, on my own, decided to add Wellbutrin XL (I had a few extras left from last year) but this did not help me. The cymbalta just never did anything so I thought that the Wellbutrin would add some punch.
I had been feeling like nothing was going to help at all. My psychiatrist asked to mull this over for a while. He called back and said we were going to try a MAO inhibitor . . . which was fine with me, at least it was a new direction.
My entire list of meds are lunesta (2mg) and provigil (only monday thru friday) at 100 mg (1/2 dose). I sometimes take fish oil and a vitamin. Sometimes, at night, I take a melatonin in addition to the Lunesta.
This is so new to me. I have a college and graduate degree, professional job . . . thinking has always come easy for me. Healthy. No real problems, thankfully.
then a 18 months or so ago, I wanted to sleep, day and night.
Doc diagnosed me as depressed, then the medicine merry go around began. On again and off again.
the person I was is a memory to me. I used to take for granted being able to think, make decisions, and just be normal. There are days now when I feel fragile, no confidence, I want to just stay alone.
As to Nardil, probably haven't given other stuff time to clear my system, but I feel as though I can't wait for Nardil to start. Reading these posts about the new formulation are disconcerting, has made me think that I need to rev things up a bit and jump to 60mg per day, now.
Tuesday and Wednesday, I took 15mg in morning and 15mg at night. Thursday and Friday, I doubled it. Maybe stupid on my part . . . I don't know, but I feel sort of desperate. I am in a hole and nardil is the rope that I am holding on to.
I so want it to help. today, thinking I was going too fast, I have gone to 45mg and will likely stay on that for a few days.
You all do not know how supporting you are - thanks.
Posted by 4WD on March 2, 2008, at 18:10:30
In reply to Nardil for Depression, posted by DontNoMuch on February 29, 2008, at 15:57:44
I will be starting Nardil on March 6th at 15mg three times a day. Maybe we can support each other though this. I am still in the middle of the Celexa washout period and am not doing too good.
Have you noticed any effects from the Nardil yet? Someone posted that it might reduce anxiety almost right away due to the GABA effects. Do you have a problem with anxiety or is it just depression?
Keep up posted on the board about your Nardil experience. Those of us who are new to Nardil need to let each other know what is going on with us. Are you having much problem with side effects?
Marsha
> After 18 months, Lexapro, Zoloft, Effexor, Wellbutrin, Cylexa, off and on and off again . . .
>
> Doc prescribed Nardil this past week. 15mg 2x a day for 7 days, then 3x a day for 7 days, then 4x a day -
>
> I am on my 4th day and keep wondering when I will feel it working. Right now, just stare at screen, feel really sad, hopeless almost.
>
> The best med I've had yet is Provigil, still taking it. 100mg / day is sufficient for me. It keeps me awake, even if I am not being very productive, beats sleeping all day.
>
> I feel as though I am in a fog.
>
> Am excited about Nardil, just really hope that it works.
Posted by DontNoMuch on March 2, 2008, at 20:43:44
In reply to Re: Nardil for Depression » DontNoMuch, posted by 4WD on March 2, 2008, at 18:10:30
My psychiatrist said that anxiety is high. A LPC said it was "through the roof" high. This was a surprise to me. I told them that I did not know it was high, it was just the way that I lived, the way that I was, like telling a fish, "hey, you are all wet." In fact, my diagnosis ended up being depression, secondary to high anxiety.
As to side effects, not sure what is due to coming off of cymbalta and what is due to depression and what is due to nardil.
Spacey. Indecisive. Lack of confidence. Stare at the screen type of thing.
However, I do sense a calmness that is most likely attributable to Nardil. I do not have any sort of high blood pressure issues, do not drink beer or wine and I can certainly live without pizza. So the hypertension spiking is not really a big concern for me, although I am mindful of this and have a bottle of meds with me just in case I start to have a reaction, an "in case of emergency" type thing.
I may have my expectations up too high, probably need to lower them some. I am hoping for a miracle in a bottle.
Today is the 6th day on nardil. As much as I wished that I could say that I feel a difference or change, I can't.
No problem with sex drive, orgasm, urination, doing number 2, etc. None of that at all.
My main concern is just feeling foggy - like I really got to think HARD to think at all.
Is that nardil? Is that depression? Not sure . . .
Posted by DontNoMuch on March 3, 2008, at 11:34:33
In reply to Re: Nardil for Depression, posted by DontNoMuch on March 2, 2008, at 20:43:44
Just came across a great article on Nardil.
Posted by 4WD on March 6, 2008, at 20:58:42
In reply to Re: Nardil for Depression » cumulative, posted by dontnomuch on March 1, 2008, at 18:51:41
>
> the person I was is a memory to me. I used to take for granted being able to think, make decisions, and just be normal. There are days now when I feel fragile, no confidence, I want to just stay alone.
>
I know how you feel. I can barely remember the person I was 4 years ago before I started getting sicker. Been on the med merry go round ever since. I spend a lot of time sitting and staring at the walls.> As to Nardil, probably haven't given other stuff time to clear my system, but I feel as though I can't wait for Nardil to start. Reading these posts about the new formulation are disconcerting, has made me think that I need to rev things up a bit and jump to 60mg per day, now.
>
> Tuesday and Wednesday, I took 15mg in morning and 15mg at night. Thursday and Friday, I doubled it. Maybe stupid on my part . . . I don't know, but I feel sort of desperate. I am in a hole and nardil is the rope that I am holding on to.I just started Nardil myself today. I started at 45 mg which is very close to what would be my standard dosage. I weigh only 51 kg. I am in the same hole as you are and I am hanging on by a thread waiting for Nardil to work. Let's hang on together, okay?
Marsha
>
This is the end of the thread.
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