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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by Lamdage22 on July 5, 2018, at 6:11:17
It is said that Rapastinel will gain approval in January 2021. Does that mean that it can be ordered via pharmacies in January?
Posted by Lamdage22 on July 5, 2018, at 7:32:43
In reply to Approval = Availability? Rapastinel, posted by Lamdage22 on July 5, 2018, at 6:11:17
What is the name of that gene test that predicts Ketamine response and therefore possibly predicts response to Rapastinel?
Posted by SLS on July 5, 2018, at 10:10:52
In reply to @SLS name of gene test predicting Ketamine respons, posted by Lamdage22 on July 5, 2018, at 7:32:43
> What is the name of that gene test that predicts Ketamine response and therefore possibly predicts response to Rapastinel?
http://www.dr-bob.org/cgi-bin/pb/mget.pl?post=/babble/20150629/msgs/1080525.html
- Scott
Posted by linkadge on July 5, 2018, at 12:10:14
In reply to Re: @SLS name of gene test predicting Ketamine respons » Lamdage22, posted by SLS on July 5, 2018, at 10:10:52
>There is no logical reason that Effexor should >work differently than an Ssri in low doses, but it >seems to for me.
From studies I read, Effexor works differently in vivo than in vitro. Human studies suggest that NRI action of Effexor is noticeable at 75mg.Keep in mind too, that the binding of the drug to a target depends on the availability of that target. Most studies of depression show that the serotonin transporter is actually downregulated. Perhaps lower availability of SERT in depression means the chemical binds more to its secondary target.
Just a thought.
Linkadge
Posted by Lamdage22 on July 14, 2018, at 5:03:41
In reply to Re: @SLS name of gene test predicting Ketamine respons » Lamdage22, posted by SLS on July 5, 2018, at 10:10:52
Is the test pricey
Posted by Lamdage22 on July 14, 2018, at 5:03:57
In reply to Re: @SLS name of gene test predicting Ketamine respons, posted by Lamdage22 on July 14, 2018, at 5:03:41
?
Posted by SLS on July 14, 2018, at 7:04:56
In reply to Re: @SLS name of gene test predicting Ketamine respons, posted by Lamdage22 on July 14, 2018, at 5:03:57
> ?
I haven't looked into it.
- Scott
Posted by TriedEveryMedication on July 14, 2018, at 15:34:22
In reply to @SLS name of gene test predicting Ketamine respons, posted by Lamdage22 on July 5, 2018, at 7:32:43
1. have 23andMe, Ancestry.com, FamilyTreeDNA, Genos done. ( I had 23andme done) (this is the costliest part)
2. after you get your results back in a couple weeks, download your raw data and upload it to Promethease.
and pay $10. After about an hour you'll get a metric truckton of medical results about know single nucleotide polymorphisms.
for 66valmet, the nucleotie is actually this one:
https://www.snpedia.com/index.php/rs6265
promethease will tell you which variant you have
HTH
Posted by bleauberry on July 19, 2018, at 9:31:45
In reply to Approval = Availability? Rapastinel, posted by Lamdage22 on July 5, 2018, at 6:11:17
I don't know, I still think some of the meds overseas are way better than the new FDA meds.
Amisulpride for one example. The USA doesn't have an antipsychotic anywhere near as good as this one for depression or dysthymia. So instead of bringing it to the USA, they instead keep it away from you and give you other new stuff that isn't as good.
I'm disappointed in our researchers. I think they are not providing us with new groundbreaking discoveries. They simply rehash old stuff to make it look new. They take the stance that manipulating levels of neurotransmitters is the entire story of depression, ignoring pathogen loads, ignoring toxicity, ignoring genetics, ignoring inflammation, ignoring the immune system, ignoring the gut lining, ignoring the adrenal glands, on and on. It's just the brain. Yeah ok. All the manipulating they do doesn't help a whole lot of people find remission. The brain is the only thing considered and in my world that is crazy wrong.
opinion
This is the end of the thread.
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Dr. Bob is Robert Hsiung, MD,
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