Posted by linkadge on July 5, 2018, at 12:10:14
In reply to Re: @SLS name of gene test predicting Ketamine respons » Lamdage22, posted by SLS on July 5, 2018, at 10:10:52
>There is no logical reason that Effexor should >work differently than an Ssri in low doses, but it >seems to for me.
From studies I read, Effexor works differently in vivo than in vitro. Human studies suggest that NRI action of Effexor is noticeable at 75mg.Keep in mind too, that the binding of the drug to a target depends on the availability of that target. Most studies of depression show that the serotonin transporter is actually downregulated. Perhaps lower availability of SERT in depression means the chemical binds more to its secondary target.
Just a thought.
Linkadge
poster:linkadge
thread:1099429
URL: http://www.dr-bob.org/babble/20180521/msgs/1099432.html