Psycho-Babble Medication Thread 515825

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Stimulant neurotoxicity - Ritalin vs. Adderall

Posted by Mr.Scott on June 19, 2005, at 23:57:30

Hello!

Does anyone have any information, experience, links or thoughts on whether low dose amphetamine vs methylphenidate is "safer" for the brain either short or long-term?

lemme know.

Thanks,

Scott

 

Re: Stimulant neurotoxicity - Ritalin vs. Adderall » Mr.Scott

Posted by Jazzed on June 20, 2005, at 7:45:26

In reply to Stimulant neurotoxicity - Ritalin vs. Adderall, posted by Mr.Scott on June 19, 2005, at 23:57:30

> Hello!
>
> Does anyone have any information, experience, links or thoughts on whether low dose amphetamine vs methylphenidate is "safer" for the brain either short or long-term?
>
> lemme know.
>
> Thanks,
>
> Scott

Lots of good information on www.addforums.com

I think you'll find both "camps", those who believe it causes problems, and those who do not. I personally do not think it causes problems. I'm on it, as well as 3 of my kids. I think it's very safe.

Jazzy

 

What about Stimulant Tolerance? » Jazzed

Posted by Mr.Scott on June 20, 2005, at 13:34:02

In reply to Re: Stimulant neurotoxicity - Ritalin vs. Adderall » Mr.Scott, posted by Jazzed on June 20, 2005, at 7:45:26

Thanks Jazzed! I'll check it out!
---------------------

How about tolerance to the antidepressant effects of adderall or any of the other stims?

Does anyone have any experience here?

Thanks,

Scott

 

Re: What about Stimulant Tolerance? » Mr.Scott

Posted by Jazzed on June 20, 2005, at 16:17:24

In reply to What about Stimulant Tolerance? » Jazzed, posted by Mr.Scott on June 20, 2005, at 13:34:02


>
> How about tolerance to the antidepressant effects of adderall or any of the other stims?
>

I have no anti-depressant effects from the Adderall at all. I don't have tolerance either,
but I've only been on it for 5 months.

Jazzy

 

Re: What about Stimulant Tolerance? » Mr.Scott

Posted by Gabbi-x-2 on June 20, 2005, at 18:38:38

In reply to What about Stimulant Tolerance? » Jazzed, posted by Mr.Scott on June 20, 2005, at 13:34:02

> Thanks Jazzed! I'll check it out!
> ---------------------
>
> How about tolerance to the antidepressant effects of adderall or any of the other stims?
>
> Does anyone have any experience here?
>
> Thanks,
>
> Scott

I've not developed a tolerance to the anti-depressant effects of dexedrine though I've been on it for about 8 years. I have learned however that klonopin, or more than 1mg a day ativan can make it feel like I have.
Of course, there *was* that first week of taking it where I was just wayyyy to happy, it's not very productive when you're just as thrilled to be sitting on the couch alone as you are actually moving. That feeling went away, but I've had no desire to increase the dose, and when I miss it for a few days I do feel a mood dip, so It's still doing something.
I'm finding out about the neurotoxicity, I'll post back.

 

Re: What about Stimulant Tolerance? » Gabbi-x-2

Posted by Mr.Scott on June 21, 2005, at 0:44:55

In reply to Re: What about Stimulant Tolerance? » Mr.Scott, posted by Gabbi-x-2 on June 20, 2005, at 18:38:38

Thanks Gabs..

hmmm...how much klonopin does it take to bring you down into the pits?

Mr.Scott

 

Re: What about Stimulant Tolerance? » Gabbi-x-2

Posted by Sarah T. on June 21, 2005, at 1:08:57

In reply to Re: What about Stimulant Tolerance? » Mr.Scott, posted by Gabbi-x-2 on June 20, 2005, at 18:38:38

Hi Gabbi,
I forgot, are you also on an antidepressant or just Dexedrine and Klonopin? How many mg of Dexedrine do you take? Forgive me if you've told me already.

Sarah T.

 

Re: Stimulant neurotoxicity - Ritalin vs. Adderall

Posted by Shawn. T. on June 21, 2005, at 14:01:52

In reply to Stimulant neurotoxicity - Ritalin vs. Adderall, posted by Mr.Scott on June 19, 2005, at 23:57:30

Looking only at neurotoxicity, Ritalin is safer. Amphetamines are associated with an increase in free radicals in the brain, but Ritalin is not. The risk of neurotoxicity is not high when only low doses are taken, but it is still wise for anyone on the drug to consume a diet rich in antioxidants.

Shawn

 

Re: What about Stimulant Tolerance? » Mr.Scott

Posted by Gabbi-x-2 on June 21, 2005, at 15:08:06

In reply to Re: What about Stimulant Tolerance? » Gabbi-x-2, posted by Mr.Scott on June 21, 2005, at 0:44:55

> Thanks Gabs..


Not a problem, Chief.

> hmmm...how much klonopin does it take to bring you down into the pits?

It's hard to remember, with Klonopin I never went all that long before taking the whole bottle:(
1 to 1.5 mgs I think, not more than that. It seemed it was the lenth of time though, not a direct result of the dose. I was fine for the first while on it, comparing it to alcohol for instance, which will leave me morbidly depressed the next day. This was insidious, so much so I didn't associate the Klonopin with the depression until I tried it for a third time.
( Okay.. maybe it makes me a bit stupid too)

And, if you would rather I didn't respond to your posts, just ignore me, I wasn't quite sure.

 

Re: What about Stimulant Tolerance? » Sarah T.

Posted by Gabbi-x-2 on June 21, 2005, at 15:12:01

In reply to Re: What about Stimulant Tolerance? » Gabbi-x-2, posted by Sarah T. on June 21, 2005, at 1:08:57

> Hi Gabbi,
> I forgot, are you also on an antidepressant or just Dexedrine and Klonopin? How many mg of Dexedrine do you take? Forgive me if you've told me already.
>
> Sarah T.

Hi Sarah

I've never told you, and I would forgive you anyway : )

I'm also on Celexa 40 mgs, and 15 mgs a day of dexedrine I take the tablets which I prefer to the spansules. I don't take Klonopin, but I do occasionally take 1mg ativan.

 

Re: What about Stimulant Tolerance? » Gabbi-x-2

Posted by Sarah T. on June 21, 2005, at 23:16:27

In reply to Re: What about Stimulant Tolerance? » Sarah T., posted by Gabbi-x-2 on June 21, 2005, at 15:12:01

Hi Gabbi,

Ah, very interesting. How long have you been on Celexa? I assume you were on Dexedrine first, because you said you'd been on it for eight years, and I think Celexa hasn't even been available for a full eight years.

Do you take Celexa at night? If so, how does it affect your sleep? When I was on it, I took it at night, but I'd always wake up at the same time each night.

Have you ever tried Lexapro?

When I was on Dexedrine, I also preferred the tablets to the spansules, unfortunately. I really wanted the spansules to work, but the manufacturer hasn't "upgraded" the release mechanism. I found the spansules unpredictable and inconsistent. Glaxo Smith Kline really should make a Dexedrine Spansule similar to Concerta or, at the very least, Adderall XR.

 

Re: What about Stimulant Tolerance? » Sarah T.

Posted by Gabbi-x-2 on June 22, 2005, at 18:25:37

In reply to Re: What about Stimulant Tolerance? » Gabbi-x-2, posted by Sarah T. on June 21, 2005, at 23:16:27

> Hi Gabbi,
A cheery hullo to you Sarah. I started a new thread down below.

 

Re: Stimulant neurotoxicity - Ritalin vs. Adderall

Posted by gabbii on June 25, 2005, at 16:25:38

In reply to Stimulant neurotoxicity - Ritalin vs. Adderall, posted by Mr.Scott on June 19, 2005, at 23:57:30

> Hello!
>
> Does anyone have any information, experience, links or thoughts on whether low dose amphetamine vs methylphenidate is "safer" for the brain either short or long-term?

Well, according to my "source" Larry, neither are harmful to the brain in therapeutic doses.
They can be damaging if you abuse them, but abuse is an entirely different bailliwick, as it's not so much the drugs but the excessive dose. That sounds kind of nonsensical, but what I mean is that calling them neurotoxic would be like saying vitamin "A" is toxic because if you take too much over a long period it may cause liver damage.

Okay, going now.


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