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Dr. Bob is Robert Hsiung, MD,
[email protected]Shown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by SadDoggie on February 25, 2005, at 2:15:50
I had said in a post last week or two weeks ago that I would be giving an opiate like hydrocodone a trial with an nmda antagonist like memantine to prevent tolerance. Well now I'm sad and pissed off because after doing more research(it's hard to do because I haven't been able to concentrate very well lately) it seems all that nmda antagonists do are block analgesic tolerance(pain), but don't do any euphoria (or antidepressant) tolerance blocking.
I've also gone back in the archives of dr-bob.org, and like one of the posters said before there was this guy who used it successfully to stop tolerance. Well in the archives that guy comes up , and guess what it's only him, with hundreds of other posts asking about this and no one ever achieving success but him. It becomes apparent why this section of the site is called "babble". Too many rumors.
I was about to get a hold of hydrocodone and even adderall or dexedrine to test out the amphetamine tolerance that some said could be stopped with an nmda antagonist, but again, going through all the archives, no one has had success with this, only rumors and b*llshit. Sorry for the bad language, I guess I'm pissed off because I was looking forward to trying these things out and now that I forced myself to concentrate better on archives, research, etc. it has become apparent that "it ain't happenin", so now I have become disillusioned. Well at least now my mind is back on Earth. One thing I will say about memantine, it sure augmented my Effexor & Klonopin, but only for a few days.
Now what I think I'll do is obsess on Electroconvulsive therapy. I don't know what else to do, I've tried most every drug on the planet in combos, you name it.
SadDoggie
Posted by medhed on February 25, 2005, at 3:05:36
In reply to Memantine and opiates and stimulants, posted by SadDoggie on February 25, 2005, at 2:15:50
Me too. I'm going to stop self medicating for a bit and try to hear what the pdoc is saying. Opiates, stims, weed, chems., they're just too up and down for a sane solution to this depression. I'm thinking MAOI I never tryed before... or ECT, ECT, ECT. MAOI scares me though, I'm not a disiplined eater and I LOVE CHEESE.
Other things I would like to try:
Lunesta
Lyrica
Provigil
Selegiline?
Posted by akabetty5 on March 3, 2005, at 16:54:31
In reply to Memantine and opiates and stimulants, posted by SadDoggie on February 25, 2005, at 2:15:50
Dear SadDoggie,
This is my first time to the board and your situation stood out to me. I'm currently in the same situation about using "hardcore" stuff to treat the chronic depression. A few months ago, I underwent gall bladder surgery (which was wierd cause I'm so young) and thought it was the answer to all my problems. The pain was gone, the chronic headaches disappeared, I felt better than I had in my entire life. I was alert, slept a normal eight hours a day, was excited about getting a job, my friends and family saw the difference and were excited, relieved and so happy for me. Two and a half weeks later I noticed the daily decline back into my normal deep depressive state. I was devastated (and still am). I feel like I've failed once again. However, I ABSOLUTELY KNOW that it wasn't a dream, and that for some reason I FELT RELIEF for that short period of time. My Pdoc explained that the morphine and analgesic's they gave me for surgery had a long lasting effect on the dopamine levels in the brain, thus giving me those two weeks of bliss. I've been BEGGING for the stuff ever since. I understand that they are addictive drugs, but it's not something that I want to take every day - maybe a dose 2 times a month? I've been researching why the drugs did what they did, why I felt sooo goood for two and a half weeks, and what other "safer, non addictive" drugs can help. I want that normal relief feeling back so bad that it hurts. Like you, I've been on every damn medication in the books and I'm tired of the mental (and physical) anguish of it all. I want to feel relieved, and it would also relieve my family's hearts too, since I know that they love me so much (and that can be a burden too...) It's so frustrating to know what made me feel like a normal happy person, yet I can't have it. What gives? I just wanted to post so that you don't feel alone. Take care and keep on keeping on. One of these days, severe mental health issues with have wonderful solutions. It's tuff to keep the hope, but Hope is what keeps us going.
This is the end of the thread.
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Dr. Bob is Robert Hsiung, MD,
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