Posted by SadDoggie on February 25, 2005, at 2:15:50
I had said in a post last week or two weeks ago that I would be giving an opiate like hydrocodone a trial with an nmda antagonist like memantine to prevent tolerance. Well now I'm sad and pissed off because after doing more research(it's hard to do because I haven't been able to concentrate very well lately) it seems all that nmda antagonists do are block analgesic tolerance(pain), but don't do any euphoria (or antidepressant) tolerance blocking.
I've also gone back in the archives of dr-bob.org, and like one of the posters said before there was this guy who used it successfully to stop tolerance. Well in the archives that guy comes up , and guess what it's only him, with hundreds of other posts asking about this and no one ever achieving success but him. It becomes apparent why this section of the site is called "babble". Too many rumors.
I was about to get a hold of hydrocodone and even adderall or dexedrine to test out the amphetamine tolerance that some said could be stopped with an nmda antagonist, but again, going through all the archives, no one has had success with this, only rumors and b*llshit. Sorry for the bad language, I guess I'm pissed off because I was looking forward to trying these things out and now that I forced myself to concentrate better on archives, research, etc. it has become apparent that "it ain't happenin", so now I have become disillusioned. Well at least now my mind is back on Earth. One thing I will say about memantine, it sure augmented my Effexor & Klonopin, but only for a few days.
Now what I think I'll do is obsess on Electroconvulsive therapy. I don't know what else to do, I've tried most every drug on the planet in combos, you name it.
SadDoggie
poster:SadDoggie
thread:463063
URL: http://www.dr-bob.org/babble/20050222/msgs/463063.html