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OCPD and overactivity of dopamine D2/D3 receptors

Posted by sukarno on April 2, 2010, at 20:39:43 [reposted on April 3, 2010, at 14:58:47 | original URL]

In reply to I think I just want control..., posted by linkadge on April 2, 2010, at 20:16:56

It's interesting that you mentioned that about high dopamine activity when depressed. I think you hit the nail right on the head. I have OCPD (Obsessive Compulsive Personality Disorder), which is basically (or should be better known as) Perfectionistic Personality Disorder. I read a medical abstract that showed high dopamine activity in the dopamine D2 and D3 receptors in folks with OCPD. The D3 receptor is associated with compulsions.

Seventy percent of people with OCPD suffer from depression too and anxiety.


diazepam (Valium) 5mg QID
tianeptine (Stablon) 12.5mg TID
Light therapy 3 hours/day
GNC Ultra Mega Gold vitamin supplement, BID

Dx: panic disorder, MDD (unipolar, melancholia), perfectionist


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poster:sukarno thread:942019
URL: http://www.dr-bob.org/babble/neuro/20100223/msgs/942019.html