Posted by yasser on March 13, 2010, at 14:17:38
In reply to D2 And 5HT2A: Dopamine Blocking And Boosting, posted by Brainbeard on July 17, 2009, at 5:32:24
ok !! i m personally taking mirtazapine (high dose) with reboxetine and selegiline (low dose). i also take some 5-htp .
thus i m attacking all monoamines with antagonising dirty receptors.mirtazapine (remeron) eliminate dirty receptors (5HT2c and 5HT2a ) and also alpha2 adreno receptor that you forgot to mention . blockade of alphaa adrenoreceptor have been shown to enhance the all 3 monoamines activity.
high synaptic level of norepinephrine (the result of alpha2 and norepinephrine reuptake inhibition by reboxetine ) accelerate dopamine and 5ht activity by stimulating alpha1 adrenoreceptors located in dopamine and 5ht cell body.
and selegiline for his cathecholamine and anti aging (ngf bdnf ....) enhancing effect in general and his prodopamine effect by his maoi b activity.
another combinaison is to take mirtazapine (high dose) with bupropion (wellbutrin), assuring a 5ht and norepinephrine and dopamine boosting effect and eliminating dirty receptors 5ht2a 5ht2c and α2.
poster:yasser
thread:907193
URL: http://www.dr-bob.org/babble/neuro/20100223/msgs/939426.html