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Re: anhedonia possibly induced by remeron » g_g_g_unit

Posted by metafunj on November 3, 2009, at 22:52:54

In reply to Re: anhedonia possibly induced by remeron, posted by g_g_g_unit on November 3, 2009, at 22:41:43

The only thing that prozac and remeron share in common to my knowledge is that they are 5 HT2C receptor antagonists. Remeron doesn't block serotonin reuptake, which prozac does. Prozac doesn't antagonizes the 5 HT2A or 5 HT3 receptors or the antihistamine receptor like remeron does.

In the following presentation Dr Stephen Stahl says that 5 HT2C inhibition leads to the release of more dopamine and norepinephrine in the Cortex.

http://books.google.com/books?id=zqvVZOea2JAC&pg=PA81&lpg=PA81&dq=stephen+stahl+5+ht2c+antagonist&source=bl&ots=nVHy2oiDoB&sig=z9IxNKFQn5KBc-D1V7cEb0w5X-k&hl=en&ei=mAfxSpyXL5XV8Aal-sT2CA&sa=X&oi=book_result&ct=result&resnum=2&ved=0CBgQ6AEwAQ#v=onepage&q=&f=false

 

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poster:metafunj thread:923965
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