Posted by catstretch on October 13, 2009, at 8:27:04
In reply to Re: How to defeat Atypical Depression?, posted by creepy on October 7, 2009, at 15:27:59
Do you have rejection sensitivity/emotional lability as one of your symptoms? Parnate seems to work better when that is the case. Some other important variables are age of onset (late adolescence?) and whether it is chronic and unremitting or goes in phases. People seem to respond better to MAOIs in the former cases.
Atypical depression is a tricky thing because the research is pretty clear that at least two different symptom clusters are combined in the one general category. It seems likely that one of the subcategories is uniquely responsive to MAOIs, but individuals who have the diagnosis as a whole aren't necessarily.
The category was also originally characterized by anxiety, so that might be plus in your case. The MAOIs seem to have some anxiolytic properties.
poster:catstretch
thread:876608
URL: http://www.dr-bob.org/babble/neuro/20090701/msgs/920777.html