Posted by metafunj on September 12, 2009, at 19:18:17
In reply to Re: Do SSRI's cause dopamine depletion, posted by Alexanderfromdenmark on September 12, 2009, at 13:00:30
I think there is some confusion. This abstract is saying that SSRIs decrease dopaminergic function.
It says that taking an SSRI decreases SERT. SERT is the serotonin transporter. With less transporters more serotonin is left in the synapse and serotonergic transmittion is enhanced.
It also says that taking an SSRI increases DAT, which is the dopamine transporter. This means that your brain on (and probably after) an SSRI is taking more dopamine up out of the synapse and decreasing dopaminergic transmittion.
I hope this helps.
poster:metafunj
thread:883495
URL: http://www.dr-bob.org/babble/neuro/20090701/msgs/916755.html