Posted by Brainbeard on September 4, 2009, at 2:09:25
In reply to Re: D2 And 5HT2A: Dopamine Blocking And Boosting, posted by jparsell82 on September 3, 2009, at 14:25:56
> And what ever happened to Ritanserin? I remember reading before that it was pretty selective for 5-ht2 and had shown anxiolytic and antidepressant effects.
I've tried finding a source on the internet, to no avail.
I find it creepy that ritanserin is known to inhibit blood platelet function, thereby increasing the risk of abnormal bleeding. (S)SRIs do that too. I wonder if any 5HT2-antagonist would decrease blood platelet function, or it is something specific to ritanserin. If not, combining an SSRI with a 5HT2A-antagonist might increase the risk of abnormal bleeding more than an SSRI alone. I wouldn't be comfortable with that.
poster:Brainbeard
thread:907193
URL: http://www.dr-bob.org/babble/neuro/20090701/msgs/915692.html