Posted by Brainbeard on July 29, 2009, at 16:26:24
In reply to Dopamine / Serotonin?, posted by SheilaC on July 26, 2009, at 9:34:33
How much time have you given the SSRIs? They tend to aggravate pain in the beginning of treatment, along with anxiety. After a couple of weeks, they are known to be effective pain-relievers.
Some drugs that work like Tramadol (SNRI) are the TCA imipramine (aka Tofranil) and especially Effexor (venlafaxine), which is very similar to Tramadol in chemical structure. For some reason Effexor, just like Tramadol, has a more immediate effect on pain than the SSRIs. Imipramine also has an immediate effect on pain. For the bladder, you would need to take Effexor in a higher dose of 75mg and up, because else you wouldn't have much noradrenergic action going on. Imipramine would possibly do the trick on lower does already.
Yep, Effexor and imipramine: these are the drugs that I would suggest for you. Effexor, like Tramadol, has a bad withdrawal syndrome for many. Imipramine could also be taken as needed, perhaps more so than Effexor.
Good luck!
poster:Brainbeard
thread:908626
URL: http://www.dr-bob.org/babble/neuro/20090701/msgs/909192.html