Why some psych drugs make my Crohn's worse

Posted by TriedEveryDrug on June 6, 2009, at 22:23:47

I have inflammatory bowel disease. Some drugs appear to make me have flare-ups. Remeron does this to me. Others, like desipramine reduce my symptoms.

I just noticed this on wikipedia about the 5-HT2A receptor:
"Other 5-HT2A agonists like LSD also have potent anti-inflammatory effects against TNF-alpha induced inflammation."
Well, TNF (tumor necrosis factor) is targeted by the latest crohn's drugs.
And sure enough, mirtazipine is a 5-HT2A antagonist.
Case closed?
(though this doesn't explain why effexor/pristiq make my crohn's worse but not as bad as remeron - I don't see anything written about them and 5-HT2a blocking action)

Thread

Why some psych drugs make my Crohn's worse TriedEveryDrug 6/6/09
Re: Why some psych drugs make my Crohn's worse desolationrower 6/7/09
Re: Why some psych drugs make my Crohn's worse SLS 6/8/09

Post a new follow-up

Notify the administrators

Start a new thread

poster:TriedEveryDrug thread:899761
URL: http://www.dr-bob.org/babble/neuro/20090129/msgs/899761.html

	for
in