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Re: Why do SSRIs SNRIs affect libido? » Jimmyboy

Posted by SLS on May 20, 2009, at 5:37:05

In reply to Re: Why do SSRIs SNRIs affect libido?, posted by Jimmyboy on May 16, 2009, at 18:32:09

> I thought Nefazodone and Cyproheptadine were 5ht2a antagonists? Is that the receptor that kills libido?
>
> also for the poster, genereic Nefazodone (Serzone) IS still available. Its made by Teva pharmaceuticals. So you could always get back on that if you had success with it.

Nefazodone is metabolized into mCPP, a drug that is known to increase libido acutely. Chronic exposure to this 5-HT2c agonist might produce some downregulation of these receptors, but there should not be the degree of sexual side effects seen in SRIs.


- Scott

 

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poster:SLS thread:879556
URL: http://www.dr-bob.org/babble/neuro/20090129/msgs/896761.html