Interleukin-6 Elevated in Suicide Attempters

Posted by Netch on March 9, 2009, at 9:56:20

Interleukin-6 Is Elevated in the Cerebrospinal Fluid of Suicide Attempters and Related to Symptom Severity:
IL-6 in CSF was significantly higher in suicide attempters than in healthy control subjects. Patients who performed violent suicide attempts displayed the highest IL-6. Furthermore, there was a significant positive correlation between MADRS scores and CSF IL-6 levels in all patients. IL-6 and TNF-α correlated significantly with 5-HIAA and HVA in CSF, but not with MHPG. Cytokine levels in plasma and CSF were not associated, and patients with increased blood-brain barrier permeability did not exhibit elevated cytokine levels.
http://www.journals.elsevierhealth.com/periodicals/bps/article/PIIS0006322309001280/abstract?rss=yes

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Interleukin-6 Elevated in Suicide Attempters Netch 3/9/09
Re: Interleukin-6 Elevated in Suicide Attempters desolationrower 3/9/09
Depression associated with elevated IL-6 levels Netch 3/21/09

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