Posted by olysi79 on May 20, 2008, at 17:54:17
In reply to Re: To Scott- the 'cross taper' faux paux » olysi79, posted by SLS on May 20, 2008, at 15:57:14
Hey Scott,
This makes sense. My brother bounced from 15 MGS of Lex to 100 MGS of Zoloft (I think) years ago.
I talked to my PDOC today and indeed, they told me they were sure it was SSRI w/d syndrome, because the Lex is stronger than the Zoloft. i was good on the 50 MGS Zoloft and switched because of some annoying, but not uber bad side effects.... my treat to endure now.
We're waiting it out for awhile for the stuff to settle and I'll have to hold still, and I'll ramp back up to 50 MGS of Zoloft in time.
I think I'll be ok... I've done the med merry go round for a long time, so I know thwe score.
Thanks for your help!!!> Some people say that Zoloft 100mg is equivalent to Lexapro 10mg. I would equate Zoloft 200mg with Lexapro 30mg. I guess it is best to use:
>
> Zoloft 37.5mg = Lexapro 5.0mg
> Zoloft 50mg = Lexapro 7.5mg
> Zoloft 100mg = Lexapro 15mg
> Zoloft 200mg = Lexapro 30mg
>
> In reality, you have to titrate clinically. I don't see that there should be any pharmacokinetic interactions between the two drugs. They don't rely on the same cytochrome P450 enzymes to metabolize them. They do have in common a small and insignificant processing through P450-3A4 the pathway.
>
>
> - Scott
poster:olysi79
thread:830094
URL: http://www.dr-bob.org/babble/neuro/20080418/msgs/830179.html