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Metformin

Posted by Dopamine123 on March 1, 2008, at 15:24:47

In reply to Re: Any meds to counteract zyprexa weight gain? » lif101part2, posted by Phillipa on February 28, 2008, at 21:10:49

Metformin might be the best thing to try of those two. It doesn't have any substantial effect on brain chemistry and is used mainly for diabetics. I think it increases insulin sensitivty and decreases glucose levels. Its also supposed to be a good anti-aging drug as well.

http://www.cincinnatichildrens.org/about/news/release/2006/12-diabetes-medicine-study.htm

"In recent years, the use of atypical antispsychotic medications to treat psychiatric illness in children and adolescents has grown dramatically. While these medications, such as Risperdal® (risperidone), Zyprexa® (olanzapine) and Seroquel® (quetiapine), effectively control many symptoms, their success is also associated with substantial weight gain and even diabetes, causing many people to stop taking them.
But a new study shows that metformin, an oral diabetes medicine that helps control blood sugar levels, not only reduces weight gain but decreases insulin sensitivity. The finding may "improve patient adherence to treatment and thus treatment outcome," according to David Klein, MD, PhD, an endocrinologist at Cincinnati Children's Hospital Medical Center and lead author of the study."

http://www.antiaging-systems.com/a2z/metformin.htm

"Metformin lowers the levels of glucose (sugar) in blood in three different ways. First, it reduces the amount of glucose produced by your liver; second, it reduces the amount of glucose absorbed from food through your stomach; and third, it improves the effectiveness of insulin in the body in reducing glucose already in the blood. This triple action makes Metformin ideal for treating type II diabetes."

"Metformin also lowers cholesterol levels and helps prevent low-density lipoproteins (bad cholesterol) from attaching to blood platelets and arteries, thereby reducing the risk of blood clotting. Due to the sugar stabilizing properties of Metformin, it is also a useful aid for dieters, helping to prevent sugar cravings."


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