Posted by bleauberry on January 26, 2008, at 19:24:58
In reply to Trivastal and Ixel - End of Day 2, So far So Good, posted by atmlady on January 26, 2008, at 9:22:39
That's awesome these meds have you feeling good. Throw a party!
I am staring at my Trivastal I've had now for about a month and too scared to try it. Any advice on that?
I'm worried about something really frieky happening. Psychosis, deep depression, severe agitation, heart pounding anxiety, stuff like that. I need more optimism and bravery.
What is the best time to take a first trial dose...morning or evening? Keep in mind I probably am going to be senstive to anything in the dopamine circuits. I am sure that is where my symptoms reside, but they have been screwed up for so long, or tweeked by an antipsychotic for so long, that I feel vulnerable to dopamine manipulation. I really want to be wrong about that. I have been med free for a year, so I think I will be sensitive to any drug.
I just finished trial 2 of Ixel. Like you, I felt goodness real fast on it. Great medicine it is. Other norepinephrine drugs such as nortriptyline or reboxetine were just horrible for me. Really bad. So how Ixel could be so good is a mystery. But it was. I am real sad that the inability to urinate was the primary side effect that made me stop. I did not have nausea, but it did hurt my appetite. I ate less. Slept great though. Real good sleep. Good energy, more sociable, less depressed, more productive at everything, more creative. I could not get past week 2 though and I was only on 25mg. At that dose I could still pee but it was hard. The problem was that with the short halflife I woke up with withdrawals each morning. Bad headache, depressed. As soon as the med kicked in after breakfast, I was all new again. Then later in the day as it wore off the mood and energy wore of too. I tried taking split doses of 12.5mg across the day and that didn't work. It had to be at least 25mg to do good.
The only other weird side effect was a slightly stuff nose. And I also had a runny nose for a couple hours after each dose. Weird.
All in all Ixel is an awesome antidepressant. Better than anything the USA has to offer. Forget the mechanisim of how it works. That is just armchair theory anyway. Serotonin, norepineprhine, ratios versus cymbalta and effexor, etc...meaningless. The drugs and the brain are much more complicated than such simplistic views. All I can say is, Ixel, it just works, and it works fast, as long as you can pee. :-)
Hey, help me out with Trivastal please.
poster:bleauberry
thread:808996
URL: http://www.dr-bob.org/babble/neuro/20080114/msgs/809085.html