Posted by Hugh on January 29, 2022, at 18:17:49
In reply to Re: Psilocybin-cannabidiol combo for depression » linkadge, posted by jay2112 on January 28, 2022, at 19:55:53
I hope linkadge will chime in here, because I haven't tried agmatine, but I have been researching it since linkadge's post about it. Agmatine is an NMDA antagonist. It "site-selectively inhibits excessive NMDA activity without disrupting normal, physiological function," like ketamine can. It appears to be safe and effective.
In a pilot study, 11 patients suffering from neuropathies took agmatine daily for 8 weeks. At the end of the 8 weeks, their pain levels were reduced an average of 46%. The dose used in this pilot study was 6 445-mg agmatine sulfate capsules per day (3 capsules twice daily, or 2 capsules thrice daily with or after meals).
This 2017 thesis from the University of Minnesota has a lot of information about agmatine:
https://conservancy.umn.edu/bitstream/handle/11299/193441/Peterson_umn_0130E_18748.pdf
poster:Hugh
thread:1118309
URL: http://www.dr-bob.org/babble/20220128/msgs/1118386.html