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Re: GABAergic hypofunction in psychosis?

Posted by undopaminergic on July 30, 2021, at 0:15:38

In reply to Re: GABAergic hypofunction in psychosis?, posted by linkadge on July 29, 2021, at 17:28:05

> As an analogy. I am not in any physical pain. This is normal. This doesn't mean I am high (like I would be on painkillers). If I took a painkiller I would still get high, even though I am not in pain. This argues that the euphoriant effect of painkillers (or benzos for that matter) are independent of their painkilling or anxiolytic effect.
>

Yes, but when pain is present, painkilling is rewarding, relatively to baseline, and is one reason you'd want to use the drug again. I agree that "addictive" is perhaps not the right term, but I don't know one that fits better.

-undopaminergic


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URL: http://www.dr-bob.org/babble/20210723/msgs/1116154.html