Posted by linkadge on March 9, 2021, at 16:50:53
In reply to Guidance on blood tests results for bupropion?, posted by Gabriel14 on March 9, 2021, at 15:47:05
Interesting.
There is only one antidepressant I know of (nortriptyline) for which a therapeutic blood level has been established.
The fact that you have lower bupropion, but higher hydroxybupropion indicates to me that you may be a faster metabolizer of bupropion. However, from what I understand, a significant degree of wellbutrin's antidepressant effect is from the metabolites. So a lower level of bupropion may not be detrimental. Personally, I would go based on therapeutic responses. Do you feel your depression is being adequately treated? If not, have you considered a higher dose? If not, have you tried other agents (i.e. SSRIs) which may augment it? For example, even a low dose of escitalopram may augment it. Zoloft may be an option too, however it can increase blood levels of bupropion (to keep in mind).
Linkadge
poster:linkadge
thread:1114047
URL: http://www.dr-bob.org/babble/20210120/msgs/1114049.html