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Re: Ketamine for depression

Posted by SLS on June 1, 2019, at 15:48:08

In reply to Re: Ketamine for depression, posted by linkadge on May 31, 2019, at 16:50:46

> People who respond to ketamine may only need to take it every few days to a week or so. For some with, say, bipolar depression, you may only need a short course to get out of depression.
>
> It really depends on your typical duration of depressive phase. You may find that lithium extends the duration of effect.
>
> The research on ketamine as an antidepressant is being written as we speak. It is a bit of no man's land, but the mechanism of antidepressant effect is supposedly unrelated to the euphorigenic properties of the drug.
>
> I've been using cannabis for (possible) bipolar depression (could also be unipolar).
>
> To be honest, its nice to take something that makes you feel better, rather than downing months of medication to wait for some faint to non-existent antidepressant effect.
>
> Linkadge

Regarding intranasal ketamine, I haven't seen any studies comparing daily dosing with intermittent dosing. What are the disadvantages of daily dosing in terms of clinical outcome? Is there evidence that intermittent dosing is better?


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poster:SLS thread:1104648
URL: http://www.dr-bob.org/babble/20190513/msgs/1104696.html