Posted by linkadge on March 27, 2016, at 13:22:55
In reply to Re: amitriptyline and apathy?, posted by B2chica on March 27, 2016, at 10:07:24
Hi SLS,
You can google "amitriptyline + trk-b". This is the receptor that amitriptyline potently binds to (like BDNF).
Personally, I love amitriptyline, because of its multiple targets. It can be a great place to start if you want stabilization of core depression symptoms. It is still considered the gold standard in terms of response and remission rates in depression. You may be able to reduce side effects by combining the amitriptyline + pristiq at less than therapeutic doses.
However, I personally believe that mood disorders become more chronic when too many medications are used for too long in too high doses. Good food and exercise can act as medication sensitizers, enhancing the brains response to chemical messages. The medications can work better when a wholistic approach is taken.I like to trade new meds for old meds, rather than layering a new one on. I tell myself that I have to give up something if I want something new. I get to use a max of 3 drugs.
Linkadge
poster:linkadge
thread:1087573
URL: http://www.dr-bob.org/babble/20160306/msgs/1087596.html