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Re: Asenapine (Saphris) for OCD » phidippus

Posted by SLS on September 15, 2015, at 21:27:37

In reply to Re: Asenapine (Saphris) for OCD » SLS, posted by phidippus on September 15, 2015, at 20:58:58

> >Don't these two drugs act in an opposite manner with respect to sigma-1 receptors? I believe sertraline is an antagonis
>
> Yup, you're right. Sertraline is a sigma 1 antagonist.
>
> Sertraline vs. Fluvoxomine in the treatment of psychotic depression:
>
> http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881105/
>
> Eric

I learned from you that fluvoxamine was uniquely effective as a SSRI to treat psychotic depression. I can't remember where I saw it, but I recall reading something suggesting that sertraline provoked akathisia more often than the other SSRIs while fluvoxamine could actually treat antipsychotic-induced akathisia.


- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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