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Re: gabergic drugs » paulb

Posted by phidippus on August 26, 2015, at 22:26:38

In reply to gabergic drugs, posted by paulb on August 20, 2015, at 14:42:28

Pregablin and Gabapentin are not GABAergic.

Tiagabine is. It is an SGRI or selective GABA reuptake inhibitor. It is only effective for anxiety in high doses. At these doses, the side effects of the drug become quite apparent.

Treatment with vigabatrin leads to an increase of GABA through inhibition of GABA-T. In studies vigabtrin treatment reduced anxiety and panic symptoms.

Eric


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