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Re: Parnate Adjuncts for Anxiety/Discipline/SelfEsteem » LazyorAnxious

Posted by SLS on August 12, 2015, at 6:31:03

In reply to Parnate Adjuncts for Anxiety/Discipline/SelfEsteem, posted by LazyorAnxious on August 11, 2015, at 17:16:51

I think Nardil would be more helpful to you in order to address your concerns.

You might want to explore the addition of nortriptyline to Parnate. Nortriptyline is usually better for anxiety than is desipramine. The combination of a MAOI with either nortriptyline and desipramine is quite safe as long as you start at a low dose and titrate gradually. You can use blood tests with nortriptyline to help guide the choice of dosage. Interestingly, nortriptyline can actually stop working if you take too much. This is what is known as a "therapeutic window".

Believe it or not, drugs like nortriptyline and desipramine can help prevent the hypertensive crisis that occurs when one ingests too much tyramine ("cheese effect"). This is because drugs that inhibit the reuptake of norepinephrine (NE) block tyramine from entering the neuron.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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