Posted by burial on February 14, 2015, at 8:54:45
In reply to Re: Effexor + Mirtazapine MORE effective than PARNATE! » Robert_Burton_1621, posted by SLS on February 14, 2015, at 7:10:34
I am on a cocktail of 300mg venlafaxine and 60mg mirtazapine and i can say it is great. I was on paroxetine plus mirtazapine before, and venlafaxine seemed way stronger than paroxetine although they both bind to NET.
http://www.ncbi.nlm.nih.gov/pubmed/18418363
According to this study, venlafaxine occupies 60% of NET and it may be that the metabolite, desvenlafaxine gives even more NET. I once read a study that desipramine occupied 80% of NET so it isn't that huge of a difference
poster:burial
thread:1040126
URL: http://www.dr-bob.org/babble/20150129/msgs/1076592.html