Posted by SLS on June 22, 2014, at 23:08:03
In reply to Re: Polypharmacy/How many is too many? » SLS, posted by MuseMemento on June 22, 2014, at 12:56:49
> Thanks, Scott. I'll seriously consider it. I'm curious as to when fetzima is going to be available in Canada. Do you think six weeks at 100 mg of clomipramine is enough to see a response if I'm likely to respond to it?
That's a good question. Some doctors thought that they could see a small improvement by the end of the first week with tricyclics. I doubt that very many of these patients had reached a stable therapeutic dosage by then. My guess is that one can experience a very short improvement during the first week that will fade until a final therapeutic dosage is reached and allowed to work for a few weeks. I think one can go as high as 250 mg/day with clomipramine if it is tolerated. If you feel absolutely nothing at 100 mg/day, I don't think you can prognosticate how you will eventually feel at 250 mg/day. I would push the dosage at the appropriate time. Because side effects can be pronounced with clomipramine, a gradual titration is suggested.
http://www.rxlist.com/anafranil-drug/indications-dosage.htm
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1066950
URL: http://www.dr-bob.org/babble/20140609/msgs/1067243.html