Posted by Tomatheus on April 10, 2014, at 16:08:09
In reply to Nardil Users, posted by kirkglen on April 7, 2014, at 11:34:16
Kirkglen,
Thanks for the report on your experiment with trying to coat your phenelzine tablets differently. Are you still noticing good results from your "polished" Greenstone phenelzine tablets?
About eight years ago, I tried putting the contents of my Nardil tablets into enteric capsules from a supplement that I had bought. As far as I know, the supplement that used the enteric capsules (PlasminPlus) is no longer being made. I noticed that the urinary retention and excessive sweating that I had been noticing on 75 mg of film-coated Nardil became much less problematic, and I also (more importantly) managed to prolong my Nardil response after I started using the enteric capsules. At the time, I was being treated for what my doctor diagnosed as recurrent major depression, with strong symptoms of diminished energy, slow thinking, and excessive sleep. Unfortunately, my responses to both the U.S. (Pfizer) Nardil and the Australian Nardil didn't last, even with the enteric capsules. I suspect that a bad batch of the Pfizer Nardil and a batch of the Australian Nardil without a desiccant in the bottle may have been why I stopped responding, but I don't know for sure if those were the reasons why.
I think that you're correct that the carnauba wax that was part of the formulation of the old Nardil helped to give the old tablets their gastro-resistant properties. Another key ingredient from the old Nardil, at least in my estimation, was pharmaceutical glaze (also known as "shellac"), which is used as an enteric coating material. From what I gathered back in 2006, pharmaceutical glaze is water-insoluble at low pH levels and water-soluble at high pH levels, which allows it to dissolve in intestinal fluids but not in the acidic environment of the stomach.
At any rate, I think it's encouraging that you noticed some improvement from "polishing" your phenelzine tablets with a product containing different waxes, and I wish you luck with trying to use some ordered carnauba wax as a coating material.
Take care,
TomatheusHas schizophrenia with strong negative and cognitive symptoms
Taking Abilify, bacopa, & vitamins B3 & D3
poster:Tomatheus
thread:1063807
URL: http://www.dr-bob.org/babble/20140328/msgs/1063975.html