Posted by poser938 on May 21, 2013, at 22:14:38
In reply to Re: Experimental AD Moves Closer To Approval, posted by SLS on May 21, 2013, at 18:48:29
> Vortioxetine is quite a bit different from other SSRIs. I think it deserves to be treated seriously as a potential treatment. For each new drug that becomes available, a certain percentage of previously treatment-resistant patients will go on to respond to it.
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> - Scott
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> =======================================
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> Dual mechanism of action
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> Vortioxetine displays two complementary mechanisms of action in vitro: inhibition of serotonin reuptake and modulation of serotonin receptor activity. In addition to blocking the serotonin transporter protein, vortioxetine acts as antagonist at 5-HT3 and 5-HT7 receptors, a partial agonist at 5-HT1B receptors and an agonist at 5-HT1A
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> =======================================Wait, I didn't see the mechanism of action.
But, for each new drug that comes out that's only slightly different from others, or is basically just a combination of 2 meds already available(Viibryd) , many will stay treatment resistant
>I was reading about an idea for a change in the way the Med system is set up. Instead of only approving drugs that are meant to be used for a certain condition, we should also make meds that target a certain possibly therapeutic area in the brain/body, and then give the doctors more freedom to come up with a very unique way to treat health problems .
Right now, they're mainly coming up with medicine that a lot of people will take and to make lots of money in return.
poster:poser938
thread:1044014
URL: http://www.dr-bob.org/babble/20130501/msgs/1044073.html